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中、西医疗法治疗白种人膝骨关节炎疗效对比研究秦新艳 李小霞 Florian BERGHEA Stefan SUTEANU


  文章编号:0255-2930(2008)06-0459-04

  中图分类号:r 246.2

  文献标志码:a

  [摘 要] 目的:比较不同疗法治疗白种人膝骨关节炎的疗效差异及安全性和耐受性。方法:将75例(90个膝关节)临床确诊为骨关节炎的患者随机分成西医组、中医组、中西医组3组。西医组:采用口服硫酸氨基葡萄糖、口服及外用非甾体类抗炎药、超声理疗等治疗;中医组:采用口服蠲痹汤,针灸、拔罐、穴位按摩和耳针治疗;中西医组:采用口服硫酸氨基葡萄糖、口服及外用非甾体类抗炎药、针灸、拔罐、穴位按摩和耳针治疗。于治疗开始后第30天、60天和90天对患者的行走痛、静息痛、夜间痛、起立痛、站立痛、晨僵、步行最长距离、日常生活能力等指标进行监测。结果:治疗90天后中西医组在疼痛的vas(视觉类推量表)评分、womac疼痛指数与僵硬感指数、lequesne疼痛指数与行走距离指数的改善方面均优于其他2组(p1,li xiao-xia1,florian berghea2,stefan suteanu3 (1.xuanwu hospital,capital medical university,beijing 100053,china;2."st maria" hospital,bucharest,romania;3.romania "carol davila" university of medicine and pharmacy)

  abstract:objective to compare the efficacy,safety and tolerability of different therapies in caucasian patients with osteoarthritis (oa) of the knee.methods seventy-five cases (90 knee joints) of osteoarthritis were randomly divided into 3 groups,western medicine group,traditional chinese medicine (tcm) group,integrated chinese and western medicine group.the western medicine group were treated with oral administration of glucosamine sulfate,oral administration and external application of non-steroid anti-inflammatory agent,ultrasound physiotherapy,etc.the tcm group were treated with oral administration of juanbi decoction,acupuncture and moxibustion,cupping,massage of acupoint and ear acupuncture.the integrated chinese and western medicine group were treated with oral administration of glucosamine sulfate,oral administration and external application of non-steroid anti-inflammatory agent,acupuncture and moxibustion,cupping,massage of acupoint and ear acupuncture.the intensity of knee joint pain on walking,resting and standing,the nocturnal pain,stiffness,the maximum walking distance and the daily living ability were monitored after 30 days,60 days and 90 days of treatment.results after 90 days of treatment,the integrated chinese and western medicine group was better than other two groups in improvement of percentages in self pain assessment with visual analog scale(vas),pain and stiffness measured by womac scale,pain and maximum walking distance measured by lequesne scale(p[1-2]。

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