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电针五脏俞对格林-巴利综合征模型兔坐骨神经电生理功能的影响王洪峰 东贵荣


  文章编号:0255-2930(2008)06-0433-03

  中图分类号:R 246.6

  文献标志码:A

  [摘 要] 目的:探讨电针膀胱经五脏俞治疗格林-巴利综合征(GBS)的作用机制。方法:选用健康大耳白兔80只,随机分成4组,即空白组、模型组、电针组、免疫球蛋白组,每组各20只。采用国际公认的P-2免疫动物模型,电针组采用电针膀胱经五脏俞进行治疗,免疫球蛋白组家兔按每日80 mg/kg给予提取的兔免疫球蛋白静脉注射进行治疗。各组分别于第7、14 d各评价1次,观察2种方法对GBS家兔坐骨神经运动传导速度(MCV)、F波的影响。结果:急性变态反应性神经炎(EAN)家兔坐骨神经MCV明显减慢,治疗第14 d时电针组家兔坐骨神经MCV较模型组明显提高(P1,DONG Gui-rong2 (1.Changchun University of TCM,Changchun 130117,China;2.Shanghai University of TCM)

  ABSTRACT:Objective To probe into the mechanism of electroacupuncture at shu-points of the five zang-organs for treatment of Guillain-Barre syndrome (GBS).Methods Eighty healthy giant-ear white rabbits were randomly divided into 4 groups,a blank group,a model group,an electroacupuncture (EA) group and an immunoglobulin group,20 rabbits in each group.The internationally recognized P-2 immune rabbit model was used in the study.The EA group were treated with EA at shu-points of the five zang-organs and the immunoglobulin group with intravenous injection of immunoglobulin 80 mg/kg/day.The sciatic nerve movement conduction velocity (MCV) and F wave incidence rate were investigated respectively at the 7th and 14th days of tre......

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