［摘要］ 目的：探讨电针促宫颈成熟的效果与机理。方法：将妊娠晚期大鼠随机分为空白组电针组蓖麻油组和临产组。用高效液相色谱法测定宫颈羟脯氨酸含量，用放射免疫分析法测定羊膜前列腺素E2(PGE2)血清白介素-6(IL-6)和白介素-8(IL-8)的含量。结果：电针显著降低了宫颈羟脯氨酸含量，显著升高了羊膜PG E2血清IL-6和IL-8的含量。结论：电针具有促宫颈成熟的作用。其机理可能与升高羊膜 PG E2血清IL-6和IL-8的含量有关。
Experimental Study on Acupuncture for Promoting Cervical Ripening in the Third Trimester of Pregnancy in Rats
Liu Zhe, Deng Haiping, Liu Hongju (Gansu College of TCM, Lanzhou 730000, China)［Abstract］ Purpose To explore the effect and mechanism of acupuncture for promoting cervical ripening.Methods Rats in the third trimester of pregnancy were divided into 4 groups: control group, electroacupuncture group, castor oil diet group and parturient group. Hydroxyproline content of cervix uteri was measured by HPLC, prostaglanding E2 (PGE2) of amnion, and serum IL-6 and IL-8 contents were determined by radioimmunoassay.Results and Conclusion Electroacupuncture can improve cervical ripening,which is related possibly to contents of increase of PGE2 in amnion,serum IL-6 and IL-8 contents.
［Key words］ Cervix Uteri/acup eff;Pregnancy Trimester, Third; Hydroxyproline/anal; Electroacupuncture